Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable...
Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Molecular imaging of matrix metalloproteinases (MMPs) may allow detection of atherosclerotic lesions vulnerable to rupture. In this study, we develop a novel radiolabelled compound that can target gelatinase MMP subtypes (MMP2/9) with high selectivity and inhibitory potency. Inhibitory potencies of several halogenated analogues of MMP subtype-selec...
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Full title
Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques
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TN_cdi_doaj_primary_oai_doaj_org_article_7454f27022434d52ba4e7bbfe447ddc7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7454f27022434d52ba4e7bbfe447ddc7
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0187767
