Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell...
Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell carcinoma
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Author / Creator
Ourailidis, Iordanis , Stögbauer, Fabian , Zhou, Yuxiang , Beck, Susanne , Romanovsky, Eva , Eckert, Stephan , Wollenberg, Barbara , Wirth, Markus , Steiger, Katja , Kuster, Bernhard , Gires, Olivier , Stenzinger, Albrecht , Schirmacher, Peter , Weichert, Wilko , Kuhn, Peer-Hendrik , Boxberg, Melanie and Budczies, Jan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tumor budding (TB) is a prognostic biomarker in HPV-negative and HPV-positive head and neck squamous cell carcinoma (HNSCC). Analyzing TCGA and CPTAC mutation, RNA, and RPPA data and performing proteomics and IHC in two independent in-house cohorts, we uncovered molecular correlates of TB in an unprecedentedly comprehensive manner.
NSD1
mutat...
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Full title
Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_74a0e834d9d644f893fd00b3b2e8caec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a0e834d9d644f893fd00b3b2e8caec
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ISSN
2397-768X
E-ISSN
2397-768X
DOI
10.1038/s41698-025-00856-2
