Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity
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Author / Creator
Zanou, Nadège , Dridi, Haikel , Reiken, Steven , Imamura de Lima, Tanes , Donnelly, Chris , De Marchi, Umberto , Ferrini, Manuele , Vidal, Jeremy , Sittenfeld, Leah , Feige, Jerome N. , Garcia-Roves, Pablo M. , Lopez-Mejia, Isabel C. , Marks, Andrew R. , Auwerx, Johan , Kayser, Bengt and Place, Nicolas
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Sustained ryanodine receptor (RyR) Ca
2+
leak is associated with pathological conditions such as heart failure or skeletal muscle weakness. We report that a single session of sprint interval training (SIT), but not of moderate intensity continuous training (MICT), triggers RyR1 protein oxidation and nitrosylation leading to calstabin1 dissoci...
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Full title
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity
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TN_cdi_doaj_primary_oai_doaj_org_article_74a4add40ec849d4a47b99015d48a534
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a4add40ec849d4a47b99015d48a534
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27422-1
