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Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in mal...

Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in mal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a58e02491542409cbfb6b455ff1d15

Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in male mice

About this item

Full title

Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in male mice

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2013-10, Vol.9 (10), p.e1003826

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

β-defensin peptides are a family of antimicrobial peptides present at mucosal surfaces, with the main site of expression under normal conditions in the male reproductive tract. Although they kill microbes in vitro and interact with immune cells, the precise role of these genes in vivo remains uncertain. We show here that homozygous deletion of a cl...

Alternative Titles

Full title

Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in male mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_74a58e02491542409cbfb6b455ff1d15

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a58e02491542409cbfb6b455ff1d15

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1003826

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