An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budd...
An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Lipid asymmetry in biological membranes is essential for various cell functions, such as cell polarity, cytokinesis, and apoptosis. P4-ATPases (flippases) are involved in the generation of such asymmetry. In
Saccharomyces cerevisiae
, the protein kinases Fpk1p/Fpk2p activate the P4-ATPases Dnf1p/Dnf2p by phosphorylation. Previously, we have s...
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An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast
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TN_cdi_doaj_primary_oai_doaj_org_article_74a8bd5f78ee4df692717e1bdefea086
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a8bd5f78ee4df692717e1bdefea086
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-69459-0