A landscape of response to drug combinations in non-small cell lung cancer
A landscape of response to drug combinations in non-small cell lung cancer
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Author / Creator
Nair, Nishanth Ulhas , Greninger, Patricia , Zhang, Xiaohu , Friedman, Adam A. , Amzallag, Arnaud , Cortez, Eliane , Sahu, Avinash Das , Lee, Joo Sang , Dastur, Anahita , Egan, Regina K. , Murchie, Ellen , Ceribelli, Michele , Crowther, Giovanna S. , Beck, Erin , McClanaghan, Joseph , Klump-Thomas, Carleen , Boisvert, Jessica L. , Damon, Leah J. , Wilson, Kelli M. , Ho, Jeffrey , Tam, Angela , McKnight, Crystal , Michael, Sam , Itkin, Zina , Garnett, Mathew J. , Engelman, Jeffrey A. , Haber, Daniel A. , Thomas, Craig J. , Ruppin, Eytan and Benes, Cyril H.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Combination of anti-cancer drugs is broadly seen as way to overcome the often-limited efficacy of single agents. The design and testing of combinations are however very challenging. Here we present a uniquely large dataset screening over 5000 targeted agent combinations across 81 non-small cell lung cancer cell lines. Our analysis reveals a profoun...
Alternative Titles
Full title
A landscape of response to drug combinations in non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Greninger, Patricia
Zhang, Xiaohu
Friedman, Adam A.
Amzallag, Arnaud
Cortez, Eliane
Sahu, Avinash Das
Lee, Joo Sang
Dastur, Anahita
Egan, Regina K.
Murchie, Ellen
Ceribelli, Michele
Crowther, Giovanna S.
Beck, Erin
McClanaghan, Joseph
Klump-Thomas, Carleen
Boisvert, Jessica L.
Damon, Leah J.
Wilson, Kelli M.
Ho, Jeffrey
Tam, Angela
McKnight, Crystal
Michael, Sam
Itkin, Zina
Garnett, Mathew J.
Engelman, Jeffrey A.
Haber, Daniel A.
Thomas, Craig J.
Ruppin, Eytan
Benes, Cyril H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_74d18fafe3754d38962c3b1365fa27b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74d18fafe3754d38962c3b1365fa27b3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39528-9
