Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Ra...
Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Mutations in the
family of genes have been consistently identified in genetic and genomic screens of autism spectrum disorder (ASD). The functional overlap of
with several other ASD-associated genes suggests synaptic dysfunction as a convergent mechanism of pathophysiology in ASD. Although many ASD-related mutations result in alterations to s...
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Full title
Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
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TN_cdi_doaj_primary_oai_doaj_org_article_74d6c9cce26d4cab991ef00801263997
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74d6c9cce26d4cab991ef00801263997
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00107
