Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models
Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models
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Switzerland: Frontiers Media S.A
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English
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Switzerland: Frontiers Media S.A
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Aminoacyl-tRNA synthetases (ARSs) play an essential role in protein synthesis, being responsible for ligating tRNA molecules to their corresponding amino acids in a reaction known as 'tRNA aminoacylation'. Separate ARSs carry out the aminoacylation reaction in the cytosol and in mitochondria, and mutations in almost all ARS genes cause pathophysiol...
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Full title
Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models
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TN_cdi_doaj_primary_oai_doaj_org_article_74ee165049d84cc4a75ed4f3764eaf56
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74ee165049d84cc4a75ed4f3764eaf56
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ISSN
1662-4548,1662-453X
E-ISSN
1662-453X
DOI
10.3389/fnins.2023.1182845
