Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in...
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
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Author / Creator
Cui, Xin , Jing, Jia , Wu, Rui , Cao, Qiang , Li, Fenfen , Li, Ke , Wang, Shirong , Yu, Liqing , Schwartz, Gary , Shi, Huidong , Xue, Bingzhong and Shi, Hang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Activation of brown fat thermogenesis increases energy expenditure and alleviates obesity. Sympathetic nervous system (SNS) is important in brown/beige adipocyte thermogenesis. Here we discover a fat-derived “adipokine” neurotrophic factor neurotrophin 3 (NT-3) and its receptor Tropomyosin receptor kinase C (TRKC) as key regulators of SNS growth an...
Alternative Titles
Full title
Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_74f4186b66d4405aa52f8f0ea75e6eb1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74f4186b66d4405aa52f8f0ea75e6eb1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25766-2
