A widespread alternate form of cap-dependent mRNA translation initiation
A widespread alternate form of cap-dependent mRNA translation initiation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Translation initiation of most mammalian mRNAs is mediated by a 5′ cap structure that binds eukaryotic initiation factor 4E (eIF4E). However, inactivation of eIF4E does not impair translation of many capped mRNAs, suggesting an unknown alternate mechanism may exist for cap-dependent but eIF4E-independent translation. We show that DAP5, an eIF4GI ho...
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A widespread alternate form of cap-dependent mRNA translation initiation
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TN_cdi_doaj_primary_oai_doaj_org_article_750fa7f27de34646a8ea452e76018a5c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_750fa7f27de34646a8ea452e76018a5c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05539-0
