Improved CUT&RUN chromatin profiling tools
Improved CUT&RUN chromatin profiling tools
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Previously, we described a novel alternative to chromatin immunoprecipitation, CUT&RUN, in which unfixed permeabilized cells are incubated with antibody, followed by binding of a protein A-Micrococcal Nuclease (pA/MNase) fusion protein (Skene and Henikoff, 2017). Here we introduce three enhancements to CUT&RUN: A hybrid protein A-Protein G-MNase co...
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Improved CUT&RUN chromatin profiling tools
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TN_cdi_doaj_primary_oai_doaj_org_article_75191d395f574c6ea9d1e96c5b479ffb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75191d395f574c6ea9d1e96c5b479ffb
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.46314