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The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients w...

The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients w...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_753fc1e1ade94842b36e1ec1512b21f5

The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Myelofibrosis (MF) is the Philadelphia-negative myeloproliferative neoplasm characterized by the worst prognosis and no response to conventional therapy. Driver mutations in
and
impact on JAK-STAT pathway activation but also on the production of reactive oxygen species (ROS). ROS play a pivotal role in inflammation-induced oxidative damage to...

Alternative Titles

Full title

The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_753fc1e1ade94842b36e1ec1512b21f5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_753fc1e1ade94842b36e1ec1512b21f5

Other Identifiers

ISSN

2076-3921

E-ISSN

2076-3921

DOI

10.3390/antiox11010113

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