Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant ta...
Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant tau transgenic mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Antibodies have been explored extensively as a potential therapeutic for Alzheimer’s disease, where amyloid-β (Aβ) peptides and the tau protein deposit in patient brains. While the major focus of antibody-based therapy development was on Aβ, arguably with limited success in clinical trials, targeting tau has become an emerging strategy, possibly ex...
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Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant tau transgenic mice
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TN_cdi_doaj_primary_oai_doaj_org_article_7542fd4f0b3143c8a94362ae7f8f1328
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7542fd4f0b3143c8a94362ae7f8f1328
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2045-2322
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2045-2322
DOI
10.1038/s41598-020-70845-x