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Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing...

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75542e73d23a4b45832f4c42a7c4b5fe

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research

About this item

Full title

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-10, Vol.14 (1), p.23068-19, Article 23068

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This report describes the development and characterization of a comprehensive collection of CHO cell glycosylation mutants with significant potential for advancing glycobiology and biotechnology. EPO-Fc and trastuzumab, two model molecules, were produced using these mutants to assess the effects of mutated glycogenes, and LC-MS/MS analysis was empl...

Alternative Titles

Full title

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_75542e73d23a4b45832f4c42a7c4b5fe

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75542e73d23a4b45832f4c42a7c4b5fe

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-73722-z

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