Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing...
Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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This report describes the development and characterization of a comprehensive collection of CHO cell glycosylation mutants with significant potential for advancing glycobiology and biotechnology. EPO-Fc and trastuzumab, two model molecules, were produced using these mutants to assess the effects of mutated glycogenes, and LC-MS/MS analysis was empl...
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Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research
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TN_cdi_doaj_primary_oai_doaj_org_article_75542e73d23a4b45832f4c42a7c4b5fe
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75542e73d23a4b45832f4c42a7c4b5fe
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-73722-z