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Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis modulating protein stabil...

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis modulating protein stabil...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_759f36e3fa0943589d54a74b765b86c1

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis modulating protein stability of β-catenin and β-catenin-mediated transcription

About this item

Full title

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis modulating protein stability of β-catenin and β-catenin-mediated transcription

Publisher

SAGE Publishing

Journal title

Therapeutic advances in chronic disease, 2020-09, Vol.11

Language

English

Formats

Publication information

Publisher

SAGE Publishing

More information

Scope and Contents

Contents

Background: Renal fibrosis is the common feature of chronic kidney disease (CKD). However, few drugs specifically target fibrogenesis due to the lack of an effective therapeutic target. Hence, it is urgent to find a therapeutic strategy that inhibits renal fibrosis. Here, we identified that poricoic acid A (PAA) as the modulator of tryptophan hydro...

Alternative Titles

Full title

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis modulating protein stability of β-catenin and β-catenin-mediated transcription

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_759f36e3fa0943589d54a74b765b86c1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_759f36e3fa0943589d54a74b765b86c1

Other Identifiers

E-ISSN

2040-6231

DOI

10.1177/2040622320962648

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