WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast can...
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
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Author / Creator
Punzi, Simona , Balestrieri, Chiara , D’Alesio, Carolina , Bossi, Daniela , Dellino, Gaetano Ivan , Gatti, Elena , Pruneri, Giancarlo , Criscitiello, Carmen , Lovati, Giulia , Meliksetyan, Marine , Carugo, Alessandro , Curigliano, Giuseppe , Natoli, Gioacchino , Pelicci, Pier Giuseppe and Lanfrancone, Luisa
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Development of metastases and drug resistance are still a challenge for a successful systemic treatment in breast cancer (BC) patients. One of the mechanisms that confer metastatic properties to the cell relies in the epithelial-to-mesenchymal transition (EMT). Moreover, both EMT and metastasis are partly modulated through epigenetic mechanisms, by...
Alternative Titles
Full title
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_75b0b17024314c6dacd446b155f5075f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75b0b17024314c6dacd446b155f5075f
Other Identifiers
ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/s13058-019-1216-y
