Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through tran...
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Somatic inactivating mutations of
ARID1A
, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidate the mechanisms underlying how
ARID1A
deleterious mutation contributes to tumorigenesis, we establish genetically engineered murine models with
Arid1a
and/or
Pten
conditional d...
Alternative Titles
Full title
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
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TN_cdi_doaj_primary_oai_doaj_org_article_75bea59380ee4facabb9a13db669ea7a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75bea59380ee4facabb9a13db669ea7a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16416-0
