RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P...
RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5
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Author / Creator
Du, Xian , Qin, Wenying , Yang, Chunyu , Dai, Lin , San, Mingkui , Xia, Yingdan , Zhou, Siyu , Wang, Mengyang , Wu, Shuang , Zhang, Shaorui , Zhou, Huiting , Li, Fangshu , He, Fang , Tang, Jingfeng , Chen, Jia-Yu , Zhou, Yu and Xiao, Rui
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Splicing factors are vital for the regulation of RNA splicing, but some have also been implicated in regulating transcription. The underlying molecular mechanisms of their involvement in transcriptional processes remain poorly understood.
Here, we describe a direct role of splicing factor RBM22 in coordinating multiple steps of RNA Polymerase II...
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Full title
RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_75c3899345da4456a07654ed5537c011
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75c3899345da4456a07654ed5537c011
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-024-03242-6
