The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy
The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Cancer is characterized as a complex disease caused by coordinated alterations of multiple signaling pathways. The Ras/RAF/MEK/ERK (MAPK) signaling is one of the best-defined pathways in cancer biology, and its hyperactivation is responsible for over 40% human cancer cases. To drive carcinogenesis, this signaling promotes cellular overgrowth by tur...
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Full title
The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_75e6085a3f3344a5aff7aec5fff06a55
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75e6085a3f3344a5aff7aec5fff06a55
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-020-00949-4
