Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antivi...
Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although annual influenza epidemics affect around 10% of the global population, current treatment options are limited and development of new antivirals is needed. Here, using quantitative phosphoproteomics, we reveal the unique phosphoproteome dynamics that occur in the host cell within minutes of influenza A virus (IAV) infection. We uncover cellu...
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Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target
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TN_cdi_doaj_primary_oai_doaj_org_article_75fc5e0fffec45b99c4b42c17dc10447
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_75fc5e0fffec45b99c4b42c17dc10447
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06119-y