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Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cell...

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_765b0f5990a74b9197e7585207bbb92c

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

About this item

Full title

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Molecular systems biology, 2015-12, Vol.11 (12), p.852-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mammalian chromosomes fold into arrays of megabase‐sized topologically associating domains (TADs), which are arranged into compartments spanning multiple megabases of genomic DNA. TADs have internal substructures that are often cell type specific, but their higher‐order organization remains elusive. Here, we investigate TAD higher‐order interaction...

Alternative Titles

Full title

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_765b0f5990a74b9197e7585207bbb92c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_765b0f5990a74b9197e7585207bbb92c

Other Identifiers

ISSN

1744-4292

E-ISSN

1744-4292

DOI

10.15252/msb.20156492

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