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TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_765c9c065e074bc09fdeae894bd6d350

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

About this item

Full title

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2023-08, Vol.18 (1), p.57-13, Article 57

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Inclusions of TAR DNA-binding protein 43 kDa (TDP-43) has been designated limbic-predominant, age-related TDP-43 encephalopathy (LATE), with or without co-occurrence of Alzheimer's disease (AD). Approximately, 30-70% AD cases present TDP-43 proteinopathy (AD-TDP), and a greater disease severity compared to AD patients without TDP-43 pathology. Howe...

Alternative Titles

Full title

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_765c9c065e074bc09fdeae894bd6d350

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_765c9c065e074bc09fdeae894bd6d350

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-023-00646-z

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