A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in card...
A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Long‐QT syndrome (LQTS) is an arrhythmogenic disorder characterised by prolongation of the QT interval in the electrocardiogram, which can lead to sudden cardiac death. Pharmacological treatments are far from optimal for congenital forms of LQTS, while the acquired form, often triggered by drugs that (sometimes inadvertently) target the cardiac hER...
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A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_767b30a7cd6e491aa4968dd31eb2d71b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_767b30a7cd6e491aa4968dd31eb2d71b
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201606260
