USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabi...
USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα
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Author / Creator
Zhuang, Ting , Zhang, Shuqing , Liu, Dongyi , Li, Zhongbo , Li, Xin , Li, Jiaoyan , Yang, Penghe , Zhang, Chenmiao , Cui, Jiayao , Fu, Mingxi , Shen, Fangyu , Yuan, Lei , Zhang, Zhao , Su, Peng , Zhu, Jian and Yang, Huijie
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
Breast cancer is the most prevalent cancer in women globally. Over-activated estrogen receptor (ER) α signaling is considered the main factor in luminal breast cancers, which can be effectively managed with selective estrogen receptor modulators (SERMs) like tamoxifen. However, approximately 30-40% of ER + breast cancer cases are recurrent after ta...
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Full title
USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα
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TN_cdi_doaj_primary_oai_doaj_org_article_768a7bedac244ef4a0d279eea2a13216
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_768a7bedac244ef4a0d279eea2a13216
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ISSN
1756-9966
E-ISSN
1756-9966
DOI
10.1186/s13046-024-03160-2