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USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabi...

USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_768a7bedac244ef4a0d279eea2a13216

USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα

About this item

Full title

USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα

Publisher

England: BioMed Central

Journal title

Journal of experimental & clinical cancer research, 2024-08, Vol.43 (1), p.249-20, Article 249

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Breast cancer is the most prevalent cancer in women globally. Over-activated estrogen receptor (ER) α signaling is considered the main factor in luminal breast cancers, which can be effectively managed with selective estrogen receptor modulators (SERMs) like tamoxifen. However, approximately 30-40% of ER + breast cancer cases are recurrent after ta...

Alternative Titles

Full title

USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_768a7bedac244ef4a0d279eea2a13216

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_768a7bedac244ef4a0d279eea2a13216

Other Identifiers

ISSN

1756-9966

E-ISSN

1756-9966

DOI

10.1186/s13046-024-03160-2

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