Comparative lipidomic and metabolomic profiling of mdx and severe mdx-apolipoprotein e-null mice
Comparative lipidomic and metabolomic profiling of mdx and severe mdx-apolipoprotein e-null mice
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Despite its notoriously mild phenotype, the dystrophin-deficient
mdx
mouse is the most common model of Duchenne muscular dystrophy (DMD). By mimicking a human DMD-associated metabolic comorbidity, hyperlipidemia, in
mdx
mice by inactivating the apolipoprotein E gene (
mdx-ApoE
) we previously reported severe myofiber damage exacer...
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Full title
Comparative lipidomic and metabolomic profiling of mdx and severe mdx-apolipoprotein e-null mice
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TN_cdi_doaj_primary_oai_doaj_org_article_768f47daaf494609a5b27f218038ba9b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_768f47daaf494609a5b27f218038ba9b
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ISSN
2044-5040
E-ISSN
2044-5040
DOI
10.1186/s13395-024-00368-w
