The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
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Author / Creator
Zhang, Fangfang , Yang, Yue , Chen, Xi , Liu, Yue , Hu, Qianxing , Huang, Bin , Liu, Yuhong , Pan, Yi , Zhang, Yanfeng , Liu, Dechen , Liang, Rui , Li, Guoqing , Wei, Qiong , Li, Ling and Jin, Liang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Despite obesity being a predisposing factor for pancreatic β-cell dysfunction and loss, the mechanisms underlying its negative effect on insulin-secreting cells remain poorly understood. In this study, we identify an islet-enriched long non-coding RNA (lncRNA), which we name β-cell function and apoptosis regulator
(βFaar)
.
βFaar
is dra...
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Full title
The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_76b0f47910f843d79f36da1d4832791e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_76b0f47910f843d79f36da1d4832791e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24302-6
