Genetic background strongly modifies the severity of symptoms of Hirschsprung disease, but not heari...
Genetic background strongly modifies the severity of symptoms of Hirschsprung disease, but not hearing loss in rats carrying Ednrb(sl) mutations
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science (PLoS)
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science (PLoS)
Subjects
More information
Scope and Contents
Contents
Hirschsprung disease (HSCR) is thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. However, it remains unknown whether the single complete deletion of important HSCR-associated genes is sufficient to result in HSCR disease. In this study, we found t...
Alternative Titles
Full title
Genetic background strongly modifies the severity of symptoms of Hirschsprung disease, but not hearing loss in rats carrying Ednrb(sl) mutations
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_76cf50493cff4ac0b61af6a7de34d19f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_76cf50493cff4ac0b61af6a7de34d19f
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0024086
