The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy
The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Tumorigenesis is highly correlated with the accumulation of mutations. The abundant and extensive DNA oxidation product, 8-Oxoguanine (8-oxoG), can cause mutations if it is not repaired by 8-oxoG repair systems. Therefore, the accumulation of 8-oxoG plays an essential role in tumorigenesis. To avoid the accumulation of 8-oxoG in the genome, base ex...
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The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_771b737871604c1d84e758de2110c3d9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_771b737871604c1d84e758de2110c3d9
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11233798