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The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_771b737871604c1d84e758de2110c3d9

The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

About this item

Full title

The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3798

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Tumorigenesis is highly correlated with the accumulation of mutations. The abundant and extensive DNA oxidation product, 8-Oxoguanine (8-oxoG), can cause mutations if it is not repaired by 8-oxoG repair systems. Therefore, the accumulation of 8-oxoG plays an essential role in tumorigenesis. To avoid the accumulation of 8-oxoG in the genome, base ex...

Alternative Titles

Full title

The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_771b737871604c1d84e758de2110c3d9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_771b737871604c1d84e758de2110c3d9

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells11233798

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