Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxyge...
Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Schizophrenia (SCZ) is a chronic neurodevelopmental psychotic disorder. The immune system and neuroinflammation seem to play a central role in the pathophysiology of SCZ. Clozapine is an effective atypical antipsychotic used for treatment-resistant SCZ. Life-threatening side effects, such as myocarditis, limit its use. We investigated the immunomod...
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Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_7746039abcda48a9bfceeadc7df44901
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7746039abcda48a9bfceeadc7df44901
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ISSN
2076-3425
E-ISSN
2076-3425
DOI
10.3390/brainsci12121703