Log in to save to my catalogue

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxyge...

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxyge...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7746039abcda48a9bfceeadc7df44901

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells

About this item

Full title

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells

Publisher

Switzerland: MDPI AG

Journal title

Brain sciences, 2022-12, Vol.12 (12), p.1703

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Schizophrenia (SCZ) is a chronic neurodevelopmental psychotic disorder. The immune system and neuroinflammation seem to play a central role in the pathophysiology of SCZ. Clozapine is an effective atypical antipsychotic used for treatment-resistant SCZ. Life-threatening side effects, such as myocarditis, limit its use. We investigated the immunomod...

Alternative Titles

Full title

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7746039abcda48a9bfceeadc7df44901

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7746039abcda48a9bfceeadc7df44901

Other Identifiers

ISSN

2076-3425

E-ISSN

2076-3425

DOI

10.3390/brainsci12121703

How to access this item