In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formul...
In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven to be accurate and reproducible. Since topical nasal formulations are applied with repeated doses...
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In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies
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TN_cdi_doaj_primary_oai_doaj_org_article_775667f3be4745bda76638b29ea4b91d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_775667f3be4745bda76638b29ea4b91d
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics13111750
