Hypoxia-Responsive Azobenzene-Linked Hyaluronate Dot Particles for Photodynamic Tumor Therapy
Hypoxia-Responsive Azobenzene-Linked Hyaluronate Dot Particles for Photodynamic Tumor Therapy
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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In this study, we developed ultra-small hyaluronate dot particles that selectively release phototoxic drugs into a hypoxic tumor microenvironment. Here, the water-soluble hyaluronate dot (dHA) was covalently conjugated with 4,4'-azodianiline (Azo, as a hypoxia-sensitive linker) and Ce6 (as a photodynamic antitumor agent), producing dHA particles wi...
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Hypoxia-Responsive Azobenzene-Linked Hyaluronate Dot Particles for Photodynamic Tumor Therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_7793f5dc2b194e29bb4d1eb55444310c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7793f5dc2b194e29bb4d1eb55444310c
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics14050928