Nanocrytals-Mediated Oral Drug Delivery: Enhanced Bioavailability of Amiodarone
Nanocrytals-Mediated Oral Drug Delivery: Enhanced Bioavailability of Amiodarone
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
The aim of this study was to improve the saturation solubility, dissolution profile and oral bioavailability of amiodarone hydrochloride (AMH), a highly lipophilic drug. Stabilizer (Pluronic F-127)-coated AMH nanocrystals (AMH-NCs) were developed by a combination of antisolvent precipitation and homogenization techniques. The optimized formulation...
Alternative Titles
Full title
Nanocrytals-Mediated Oral Drug Delivery: Enhanced Bioavailability of Amiodarone
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_77b95f7f4c2a4517a0958063fe7e3604
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77b95f7f4c2a4517a0958063fe7e3604
Other Identifiers
ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics14061300
