New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbaz...
New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbazone FA4
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
A new sigma-2 (σ2) receptor ligand (FA4) was efficiently synthesized and evaluated for cytotoxic, proapoptotic, and antimigratory activity on pancreatic ductal adenocarcinoma (PDAC) primary cell cultures, which restrained the aggressive and chemoresistant behavior of PDAC. This compound showed relevant antiproliferative activity with half maximal i...
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Full title
New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbazone FA4
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TN_cdi_doaj_primary_oai_doaj_org_article_77d58d0d3450434baa4df90017374e7e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77d58d0d3450434baa4df90017374e7e
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27051682
