Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemoth...
Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemotherapy in early stage luminal B breast cancer, a randomized phase II trial
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Author / Creator
De Caluwé, Alex , Buisseret, Laurence , Poortmans, Philip , Van Gestel, Dirk , Salgado, Roberto , Sotiriou, Christos , Larsimont, Denis , Paesmans, Marianne , Craciun, Ligia , Stylianos, Drisis , Vandekerckhove, Christophe , Reyal, Fabien , Isabelle, Veys , Eiger, Daniel , Piccart, Martine , Romano, Emanuela and Ignatiadis, Michail
Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
Residual breast cancer after neo-adjuvant chemotherapy (NACT) predicts disease outcome and is a surrogate for survival in aggressive breast cancer (BC) subtypes. Pathological complete response (pCR) rate, however, is lower for luminal B BC in comparison to the triple negative (TNBC) and HER2+ subtypes. The addition of immune checkpoint blockade (IC...
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Full title
Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemotherapy in early stage luminal B breast cancer, a randomized phase II trial
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TN_cdi_doaj_primary_oai_doaj_org_article_77e1e848595f46df8edd12cb7e91b490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_77e1e848595f46df8edd12cb7e91b490
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-021-08601-1