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Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to...

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_781ea0c332464bf09c872f6a6b3d11ae

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors

About this item

Full title

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors

Publisher

England: BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2019-12, Vol.21 (1), p.146-146, Article 146

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Addition of CDK4/6 inhibitors (CDK4/6i) to endocrine therapy significantly increased progression-free survival, leading to their approval and incorporation into the metastatic breast cancer treatment paradigm. With these inhibitors being routinely used for patients with advanced estrogen receptor-positive (ER+) breast cancer, resistance to these ag...

Alternative Titles

Full title

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_781ea0c332464bf09c872f6a6b3d11ae

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_781ea0c332464bf09c872f6a6b3d11ae

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/s13058-019-1230-0

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