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Tuning the B-CLL microenvironment: evidence for BAG3 protein- mediated regulation of stromal fibrobl...

Tuning the B-CLL microenvironment: evidence for BAG3 protein- mediated regulation of stromal fibrobl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_781eb40488154d1d9d949f60a66c1134

Tuning the B-CLL microenvironment: evidence for BAG3 protein- mediated regulation of stromal fibroblasts activity

About this item

Full title

Tuning the B-CLL microenvironment: evidence for BAG3 protein- mediated regulation of stromal fibroblasts activity

Publisher

London: Nature Publishing Group UK

Journal title

Cell death discovery, 2024-08, Vol.10 (1), p.383-11, Article 383

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Bcl2-associated athanogene-3 (BAG3) protein, a critical regulator of cellular survival, has been identified as a potential therapeutic target in various malignancies. This study investigates the role of BAG3 within stromal fibroblasts and its interaction with B-cell chronic lymphocytic leukemia (B-CLL) cells. Previous research demonstrated that...

Alternative Titles

Full title

Tuning the B-CLL microenvironment: evidence for BAG3 protein- mediated regulation of stromal fibroblasts activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_781eb40488154d1d9d949f60a66c1134

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_781eb40488154d1d9d949f60a66c1134

Other Identifiers

ISSN

2058-7716

E-ISSN

2058-7716

DOI

10.1038/s41420-024-02153-6

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