RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes
RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes
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Author / Creator
Kou, Tiantian , Kang, Lan , Zhang, Bin , Li, Jiaqi , Zhao, Baohong , Zeng, Wenwen and Hu, Xiaoyu
Publisher
Cambridge: eLife Sciences Publications Ltd
Journal title
Language
English
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Publication information
Publisher
Cambridge: eLife Sciences Publications Ltd
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Scope and Contents
Contents
Notch-RBP-J signaling plays an essential role in the maintenance of myeloid homeostasis. However, its role in monocyte cell fate decisions is not fully understood. Here, we showed that conditional deletion of transcription factor RBP-J in myeloid cells resulted in marked accumulation of blood Ly6C
lo
monocytes that highly expressed chemokine...
Alternative Titles
Full title
RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_782656cac1bb4b678edac60c36e4f9a9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_782656cac1bb4b678edac60c36e4f9a9
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.88135
