DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic inst...
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
About this item
Full title
Author / Creator
Batra, Rajbir Nath , Lifshitz, Aviezer , Vidakovic, Ana Tufegdzic , Chin, Suet-Feung , Sati-Batra, Ankita , Sammut, Stephen-John , Provenzano, Elena , Ali, H. Raza , Dariush, Ali , Bruna, Alejandra , Murphy, Leigh , Purushotham, Arnie , Ellis, Ian , Green, Andrew , Garrett-Bakelman, Francine E. , Mason, Chris , Melnick, Ari , Aparicio, Samuel A. J. R. , Rueda, Oscar M. , Tanay, Amos and Caldas, Carlos
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA methylation is aberrant in cancer, but the dynamics, regulatory role and clinical implications of such epigenetic changes are still poorly understood. Here, reduced representation bisulfite sequencing (RRBS) profiles of 1538 breast tumors and 244 normal breast tissues from the METABRIC cohort are reported, facilitating detailed analysis of DNA...
Alternative Titles
Full title
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
Authors, Artists and Contributors
Author / Creator
Lifshitz, Aviezer
Vidakovic, Ana Tufegdzic
Chin, Suet-Feung
Sati-Batra, Ankita
Sammut, Stephen-John
Provenzano, Elena
Ali, H. Raza
Dariush, Ali
Bruna, Alejandra
Murphy, Leigh
Purushotham, Arnie
Ellis, Ian
Green, Andrew
Garrett-Bakelman, Francine E.
Mason, Chris
Melnick, Ari
Aparicio, Samuel A. J. R.
Rueda, Oscar M.
Tanay, Amos
Caldas, Carlos
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7832b4cd7ff242839e4e5e73265c879e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7832b4cd7ff242839e4e5e73265c879e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25661-w
