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Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP ta...

Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP ta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_787c5ae4190e406a97b983bb6fe7572b

Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

About this item

Full title

Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-07, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Tuberous sclerosis complex (TSC) is a genetic disorder that is associated with multiple neurological manifestations. Previously, we demonstrated that
loss in cerebellar Purkinje cells (PCs) can cause altered social behavior in mice. Here, we performed detailed transcriptional and translational analyses of
-deficient PCs to understand the mole...

Alternative Titles

Full title

Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_787c5ae4190e406a97b983bb6fe7572b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_787c5ae4190e406a97b983bb6fe7572b

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.67399

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