Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbo...
Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The global spread of Zika virus (ZIKV) and its unexpected association with congenital defects necessitates the rapid development of a safe and effective vaccine. Here we report the development and characterization of a recombinant chimeric ZIKV vaccine candidate (termed ChinZIKV) that expresses the prM-E proteins of ZIKV using the licensed Japanese...
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Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
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TN_cdi_doaj_primary_oai_doaj_org_article_788df413c3c54bebaab8d4b979a10833
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_788df413c3c54bebaab8d4b979a10833
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-02975-w