Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using g...
Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
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Author / Creator
Li, Danyang , Pain, Oliver , Fabbri, Chiara , Wong, Win Lee Edwin , Lo, Chris Wai Hang , Ripke, Stephan , Cattaneo, Annamaria , Souery, Daniel , Dernovsek, Mojca Z. , Henigsberg, Neven , Hauser, Joanna , Lewis, Glyn , Mors, Ole , Perroud, Nader , Rietschel, Marcella , Uher, Rudolf , Maier, Wolfgang , Baune, Bernhard T. , Biernacka, Joanna M. , Bondolfi, Guido , Domschke, Katharina , Kato, Masaki , Liu, Yu-Li , Serretti, Alessandro , Tsai, Shih-Jen , Weinshilboum, Richard , McIntosh, Andrew M. , Lewis, Cathryn M. , the GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to understand the impact of genetic variations on antidepressant response. In this study, individual clinical and genetic data from...
Alternative Titles
Full title
Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Authors, Artists and Contributors
Author / Creator
Pain, Oliver
Fabbri, Chiara
Wong, Win Lee Edwin
Lo, Chris Wai Hang
Ripke, Stephan
Cattaneo, Annamaria
Souery, Daniel
Dernovsek, Mojca Z.
Henigsberg, Neven
Hauser, Joanna
Lewis, Glyn
Mors, Ole
Perroud, Nader
Rietschel, Marcella
Uher, Rudolf
Maier, Wolfgang
Baune, Bernhard T.
Biernacka, Joanna M.
Bondolfi, Guido
Domschke, Katharina
Kato, Masaki
Liu, Yu-Li
Serretti, Alessandro
Tsai, Shih-Jen
Weinshilboum, Richard
McIntosh, Andrew M.
Lewis, Cathryn M.
the GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
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Primary Identifiers
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TN_cdi_doaj_primary_oai_doaj_org_article_78b6105acfec40b1aa485bf11a65c749
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78b6105acfec40b1aa485bf11a65c749
Other Identifiers
ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-024-02981-1
