Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
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Author / Creator
Duffy, Megan F , Collier, Timothy J , Patterson, Joseph R , Kemp, Christopher J , Luk, Kelvin C , Tansey, Malú G , Paumier, Katrina L , Kanaan, Nicholas M , Fischer, D Luke , Polinski, Nicole K , Barth, Olivia L , Howe, Jacob W , Vaikath, Nishant N , Majbour, Nour K , El-Agnaf, Omar M A and Sortwell, Caryl E
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Converging evidence suggests a role for microglia-mediated neuroinflammation in Parkinson's disease (PD). Animal models of PD can serve as a platform to investigate the role of neuroinflammation in degeneration in PD. However, due to features of the previously available PD models, interpretations of the role of neuroinflammation as a contributor to...
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Full title
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_78b82214e6ad41e9bc7e34dc3be1cf71
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78b82214e6ad41e9bc7e34dc3be1cf71
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-018-1171-z
