Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination...
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the central nervous system (CNS). Although studies have demonstrated that microglia facilitate remyelination in demyelinating diseases, the underlying mechanisms are still not fully characterized. We found that aryl hydrocarbon receptor (AhR), an environment sensor, was up...
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Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination
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TN_cdi_doaj_primary_oai_doaj_org_article_78ded7c098b9420fa6ec5ddad818fc9a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78ded7c098b9420fa6ec5ddad818fc9a
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02764-3
