High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediate...
High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials
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Full title
Author / Creator
Reeves, Daniel B. , Mayer, Bryan T. , deCamp, Allan C. , Huang, Yunda , Zhang, Bo , Carpp, Lindsay N. , Magaret, Craig A. , Juraska, Michal , Gilbert, Peter B. , Montefiori, David C. , Bar, Katharine J. , Cardozo-Ojeda, E. Fabian , Schiffer, Joshua T. , Rossenkhan, Raabya , Edlefsen, Paul , Morris, Lynn , Mkhize, Nonhlanhla N. , Williamson, Carolyn , Mullins, James I. , Seaton, Kelly E. , Tomaras, Georgia D. , Andrew, Philip , Mgodi, Nyaradzo , Ledgerwood, Julie E. , Cohen, Myron S. , Corey, Lawrence , Naidoo, Logashvari , Orrell, Catherine , Goepfert, Paul A. , Casapia, Martin , Sobieszczyk, Magdalena E. , Karuna, Shelly T. and Edupuganti, Srilatha
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The Antibody Mediated Prevention (AMP) trials (NCT02716675 and NCT02568215) demonstrated that passive administration of the broadly neutralizing monoclonal antibody VRC01 could prevent some HIV-1 acquisition events. Here, we use mathematical modeling in a post hoc analysis to demonstrate that VRC01 influenced viral loads in AMP participants who acq...
Alternative Titles
Full title
High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials
Authors, Artists and Contributors
Author / Creator
Mayer, Bryan T.
deCamp, Allan C.
Huang, Yunda
Zhang, Bo
Carpp, Lindsay N.
Magaret, Craig A.
Juraska, Michal
Gilbert, Peter B.
Montefiori, David C.
Bar, Katharine J.
Cardozo-Ojeda, E. Fabian
Schiffer, Joshua T.
Rossenkhan, Raabya
Edlefsen, Paul
Morris, Lynn
Mkhize, Nonhlanhla N.
Williamson, Carolyn
Mullins, James I.
Seaton, Kelly E.
Tomaras, Georgia D.
Andrew, Philip
Mgodi, Nyaradzo
Ledgerwood, Julie E.
Cohen, Myron S.
Corey, Lawrence
Naidoo, Logashvari
Orrell, Catherine
Goepfert, Paul A.
Casapia, Martin
Sobieszczyk, Magdalena E.
Karuna, Shelly T.
Edupuganti, Srilatha
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_794805ba580c4e44895b377fd359c2eb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_794805ba580c4e44895b377fd359c2eb
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43384-y
