Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer’s disease-like neuroinf...
Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer’s disease-like neuroinflammation and cognitive impairment
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Human genetic association studies point to immune response and lipid metabolism, in addition to amyloid-beta (Aβ) and tau, as major pathways in Alzheimer's disease (AD) etiology. Accumulating evidence suggests that chronic neuroinflammation, mainly mediated by microglia and astrocytes, plays a causative role in neurodegeneration in AD. Our group an...
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Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer’s disease-like neuroinflammation and cognitive impairment
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TN_cdi_doaj_primary_oai_doaj_org_article_7968af0cadaf4aba9fed3628e5117c8b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7968af0cadaf4aba9fed3628e5117c8b
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-021-00488-7
