Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
About this item
Full title
Author / Creator
Pateraki, Irini , Andersen-Ranberg, Johan , Jensen, Niels Bjerg , Wubshet, Sileshi Gizachew , Heskes, Allison Maree , Forman, Victor , Hallström, Björn , Hamberger, Britta , Motawia, Mohammed Saddik , Olsen, Carl Erik , Staerk, Dan , Hansen, Jørgen , Møller, Birger Lindberg , Hamberger, Björn and USDOE Bioenergy Research Centers (BRC) (United States). Great Lakes Bioenergy Research Center (GLBRC)
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
Forskolin is a unique structurally complex labdane-type diterpenoid used in the treatment of glaucoma and heart failure based on its activity as a cyclic AMP booster. Commercial production of forskolin relies exclusively on extraction from its only known natural source, the plant
, in which forskolin accumulates in the root cork. Here, we report...
Alternative Titles
Full title
Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
Authors, Artists and Contributors
Author / Creator
Andersen-Ranberg, Johan
Jensen, Niels Bjerg
Wubshet, Sileshi Gizachew
Heskes, Allison Maree
Forman, Victor
Hallström, Björn
Hamberger, Britta
Motawia, Mohammed Saddik
Olsen, Carl Erik
Staerk, Dan
Hansen, Jørgen
Møller, Birger Lindberg
Hamberger, Björn
USDOE Bioenergy Research Centers (BRC) (United States). Great Lakes Bioenergy Research Center (GLBRC)
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_79be50ee60af4d97984db820314ab6a2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_79be50ee60af4d97984db820314ab6a2
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.23001
