Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cure...
Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy
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England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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BackgroundPoorly immunogenic tumors are hardly responsive to immunotherapies such as immune checkpoint blockade (ICB) and are, therefore, a therapeutic challenge. Combination with other immunotherapies and/or immunogenic therapies, such as radiotherapy (RT), could make these tumors more immune responsive. We have previously shown that the immunocyt...
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Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_79cc56a05cf2418c8eb72e923bf9ce7a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_79cc56a05cf2418c8eb72e923bf9ce7a
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001764
