Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Ech...
Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine
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Author / Creator
Yu, Yingfang , Li, Jun , Wang, Weisi , Wang, Tian , Qi, Wenjing , Zheng, Xueting , Duan, Lei , Chen, Jiaxu , Li, Shizhu , Han, Xiumin , Zhang, Wenbao and Duan, Liping
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Cystic echinococcosis (CE) is a life-threatening zoonosis caused by the larval form of Echinococcus granulosus tapeworm. Our previous study showed that an approved drug pyronaridine (PND) is highly effective against CE, both in vitro and in an animal model. To identify possible target genes, transcriptome analysis was performed with E. granulosus s...
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Full title
Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7a0dcad7cfea40569994c3734bd30615
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a0dcad7cfea40569994c3734bd30615
Other Identifiers
ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-021-07875-w
