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The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212...

The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a2581e34c8d442186c4a612aaed5c0f

The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation

About this item

Full title

The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation

Publisher

Switzerland: MDPI AG

Journal title

Brain sciences, 2024-06, Vol.14 (7), p.668

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Gi-coupled receptors, particularly cannabinoid receptors (CBRs), are considered perspective targets for treating brain pathologies, including epilepsy. However, the precise mechanism of the anticonvulsant effect of the CBR agonists remains unknown. We have found that WIN 55,212-2 (a CBR agonist) suppresses the synchronous oscillations of the intrac...

Alternative Titles

Full title

The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7a2581e34c8d442186c4a612aaed5c0f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a2581e34c8d442186c4a612aaed5c0f

Other Identifiers

ISSN

2076-3425

E-ISSN

2076-3425

DOI

10.3390/brainsci14070668

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