The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212...
The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Gi-coupled receptors, particularly cannabinoid receptors (CBRs), are considered perspective targets for treating brain pathologies, including epilepsy. However, the precise mechanism of the anticonvulsant effect of the CBR agonists remains unknown. We have found that WIN 55,212-2 (a CBR agonist) suppresses the synchronous oscillations of the intrac...
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The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation
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TN_cdi_doaj_primary_oai_doaj_org_article_7a2581e34c8d442186c4a612aaed5c0f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a2581e34c8d442186c4a612aaed5c0f
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2076-3425
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2076-3425
DOI
10.3390/brainsci14070668