Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms underlying cachexia remain poorly understood. Leukemia inhibitory factor (LIF), a multi-functional cytokine, has been suggested as a cachexia-inducing factor. In a transgenic mouse model with conditional LIF e...
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Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_7a74af24de084f61a52f3aa01ccc642c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a74af24de084f61a52f3aa01ccc642c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-44924-w
